NMN supplements are absorbed in our cells with the help of the molecular transporter that is embedded in our cell surface. As they are smaller than NAD+, nicotinamide mononucleotide molecules can easily be absorbed in our cells. NAD+ can’t enter our body very easily due to this barrier of a cell membrane. This membrane has got a waterless space that stops polar molecules, big molecules, and ions to enter our body without transporters. Earlier it was reported that NMN gets altered before they form new cells but the latest study suggests that it enter the cells through an NMN transporter in our cellular membrane.
Even NMN injections can increase NAD+ compound in many different areas of our body that includes fat tissue, heart, eyes, pancreas, kidneys, testes, skeletal muscle, and blood vessels. It was reported that the administration of NMN orally improved NAD+ level in 15 minutes among mice.
What Lies Ahead in NMN?
The studies showed in animals promising therapeutic substances NMN showed, the researchers are trying to know how the molecule cell works in our human body too. The clinical trial demonstrated that it is a safe molecule & well-tolerated in the given dosage. There were many studies and trials on the way that will put more emphasis on how it works. It’s the most fascinating and amazing molecule that we have to learn so much about.
As per the research, NMN and NR precursors can be viewed as the production of the NAD+ supplements, improving NAD+ concentrations. The researchers have concluded that feeding and administering the NAD+ supplements directly isn’t the practical way out. And NAD+ molecules can’t easily cross or enter cells, so it will not positively affect the metabolism. But, precursor molecules should be used if you want to improve bioavailable NAD+ levels.
We can conclude that NAD+ can’t be directly used as the supplement, as it isn’t absorbed very easily. And NAD+ precursors are absorbed very easily than NAD+ as well as prove highly effective supplements out there. So, these are some important facts that you need to learn about nicotinamide mononucleotide.